MSM Product Buyer’s Guide (updated May 2024)

Product Comparison

Approved Science MSM
Douglas Laboratories MSM Capsules
Designs for Health MSM
KALA Health MSMPure
Provides at least a 2,000mg daily serving of MSM
Contains OptiMSM®, GRAS-designated for purity
Does not include heavy metals, contaminants or impurities
Contains Ingredient for enhancing absorption and utilization of MSM
No additives, preservatives, or artificial ingredients
Made in the USA
Money-back guarantee

MSM Report


Rating: Excellent


Money Back Guarantee
Consumer Feedback
Company Reputation

Editor’s Choice

Approved Science MSM

If you are looking to improve your overall health by strengthening connective tissue for a difference you can feel throughout your body, then Approved Science MSM is something that deserves your undivided attention. Of all the MSM supplements currently available on the market, this is the one that deserves a closer look and very likely, the one that will change your life!

It contains the highest quality, clinically-proven, OptiMSM® which is the only MSM to have the GRAS (generally recognized as safe) designation for its purity. The unique 4-stage distillation process ensures a product that really works because it is free of impurities that make other products less effective. It was the only product we found that contains a whopping 2000mg daily serving of MSM for reducing inflammation, improving joint health, clearing skin irritations, boosting the immune system and easing allergy symptoms. In addition, it contains BioPerine®, a thermogenic ingredient that enhances the body’s ability to absorb and utilize MSM for greater health benefits. It does not contain any additives or preservatives and is totally 100% safe to use with no long-term side effects.

Quality: Approved Science MSM contains high-grade, natural, clinically-verified ingredients that are GMP certified, FDA registered and contains OptiMSM® which is third-party tested for 100% purity. 

Reputation: Their reputation is top quality. This manufacturer has several third-party monitoring services, including buySAFE, Norton, and Trustee, as well as an A+ rating from the quality monitoring company QualityTrusted.

Money Back Guarantee: Every item sold is supported by a 60-day 100% money-back guarantee. Such guarantees from manufacturers show strong confidence in their products’ ability to deliver results. Great news for consumers.

What’s more, they are well known in the industry and an established company that provides great customer support service, secure and easy checkout as well as prompt, efficient delivery.

Their commitment to the health industry and consumers is excellent, providing further qualification of efficacy by producing their products in an FDA registered laboratory.

If you are looking for a product that ticks all the boxes for an effective MSM supplement, from an established reputable company with an excellent money-back guarantee, this is the supplement for you.

It would be good to note that, due to high demand, Approved Science MSM is often sold out. To avoid having to back order, don’t hesitate to make that purchase when you see it in stock.

See The Full Review


Rating: Good



Douglas Laboratories MSM Capsules

Promoted as a health product to help support healthy connective tissues, lungs and joints, Douglas Laboratories MSM Capsules is our next product up for review. This manufacturer has a good reputation and this product contains OptiMSM® for the purest MSM on the market. But is this enough to compensate for this product’s low daily serving? 

When reviewing this product, we were pleased to see a price tag that suggests quality – not cheap, but definitely affordable. We appreciated that this product is formulated with OptiMSM® as it has a multi-stage distillation process and each batch is third-party tested for purity. However, it is unclear to us if this double-strength formula will actually be effective. With 750mg of MSM, Douglas Laboratories has manufactured a product that contains less than half of the dose of our Editor’s #1 Choice. 

Additionally, there is no thermogenic ingredient added to the formula which would serve to boost the bioavailability of the MSM ensuring that sulfur is delivered to the entire body more effectively. Still, consumers might be interested in trying this product for themselves as it is certainly is a safe option as far as we can see. However, there are 2 caveats. One is that there is gelatin in this product and therefore not suitable for vegans, vegetarians or people who follow kosher or halal rules. The second caveat is that because Douglas Laboratories sell directly to healthcare providers, it is not possible to purchase from the manufacturer themselves. While it is possible to buy from Amazon, it is unclear if the return policy would still apply. Even if it does, consumers should be aware that it is only applicable for 30 days and requires authorization. Continue reading our review to see if this product is worth your time and money.

Click here to read the full review


Rating: OK


Designs for Health MSM

Designs for Health MSM claims to be a company that is trusted by over 50,000 practitioners. This is quite a bold claim! In our review of this MSM product, we were a bit puzzled and interested to know what all those practitioners would think of this formulation. We can’t speak for all of their products, but this one seemed to be missing some crucial aspects for a quality MSM supplement.  

The most troubling aspect of this product is the absence of OptiMSM®. As this is the top MSM on the market and known for its high quality and third-party testing, it was disappointing not to see it here. We would have hoped to see some transparency from the manufacturer as to their process of purifying their MSM. While distillation is the preferred method of isolating MSM, it is also a lot more costly. When companies do not disclose their purification process, we assume they use the more inexpensive route of crystallization. Unfortunately, part of this method includes cooling down the MSM which can lead to occlusions that trap contaminants and lead to an impure product. 

So what exactly is in these pills? They contain 1 gram of MSM but may also contain impurities such as heavy metals. At best, these can get in the way of an effective product. At worst, they can cause serious harm if you ingest them. We examined customer reviews but there were too few for us to get a good idea of what consumers can expect. We were pleased to see that there is a return policy but it is only for 30 days and only applicable for unopened bottles so it is not possible to try this product out to find out if it works. Continue reading our full review to see the full picture of this product.

Click here to read the full review


What You’ll Discover:

Which MSM supplement is the BEST BUY and comes with a great GUARANTEE!
Which formula and ingredients are the most EFFECTIVE and work the fastest?
How NOT to get ripped off! BE AWARE of poor quality and cheap products.

Top 6 Items to Consider:

  1. Ingredients
  2. Cost Per Serving
  3. Product’s Testing Results
  4. Company’s Reputation
  5. Consumer Reviews
  6. Return Policy & Satisfaction Guarantee

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