MSM Product Buyer’s Guide (updated May 2024)

Approved Science MSM Review



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Overall Rating 
Our research has shown that this manufacturer has created a product born from science and clinical data. We found that this product provides 100% OptiMSM® for the purest and most effective MSM known worldwide for optimal health benefits. This top-quality formula boasts the addition of BioPerine®, a patented black pepper extract clinically proven to boost nutrition absorption for faster results such as relieving joint and muscle pain, enhancing skin health, managing arthritis symptoms and boosting immune health. We liked that it offers a 60-day money-back guarantee if you are not happy with the results.  

Why do we recommend Approved Science MSM?

Main Benefits:

  • It contains 100% OptiMSM®, a patented methylsulfonylmethane (MSM) clinically proven for its purity, consistency and efficacy.
  • It provides a powerful daily serving of 2,000mg OptiMSM® which is double what most brands offer. 
  • It contains a multi-stage distillation process to eliminate contaminants for optimal safety and the most effective health benefits.   
  • It undergoes third-party testing to ensure 100% purity.
  • It is made in the USA, unlike many other companies that choose to crystallize their MSM in Asia.
  • It does not contain any preservatives, artificial colorings, hormones, or unnecessary ingredients that may dilute the efficacy of the product.
  • We found so many supportive consumer reviews from users who had experienced excellent results, some within as little as a week.
  • Its daily suggested serving is the optimal potency as recommended by doctors for effectiveness and is supported by extensive clinical research trials and studies.
  • This manufacturer’s customer service is second to none, it provides excellent support and help. Furthermore, it offers an excellent money-back guarantee if customers are not happy with their results.


Methylsulfonylmethane, more widely known as MSM, is a natural compound that contains sulfur and is found naturally in humans, plants and animals. There are so many positive health implications for the body as sulfur is involved in many important functions in the body. From alleviating arthritis symptoms to improving skin health, MSM works its magic largely by reducing inflammation and boosting antioxidant activity through our bodily systems. It is important to note that not all MSM supplements are created equally. The purity and dosage of MSM makes a huge difference in how they will be utilized by the body in the same way to provide the most effective results you are searching for. There are several key studies that help pinpoint the way when it comes to finding the most effective MSM supplement to optimize your health. 

First and foremost, MSM supplements must contain OptiMSM®. This is the only MSM that is GRAS-designated for the purest compound. The manufacturer of OptiMSM®,  Bergstrom Nutrition, uses a unique, proprietary 4-stage distillation process in order to purify effectively, ensuring there are no contaminants. Every batch of OptiMSM® is third-party tested to ensure the highest quality MSM possible. It is also made in the USA and is manufactured in a cGMP-certified, ISO-registered facility. If a product does not contain OptiMSM®, it means it will not be as effective, plain and simple.

Secondly, MSM supplements should contain at least 2000mg of MSM. Many supplements will offer only half this amount and therefore will be able to deliver on the promised health benefits. Taking an effective dose is the only way to get noticeable results.

Thirdly, the inclusion of BioPerine® has been shown to increase bioavailability (absorption), ensuring that you feel the effects sooner, stronger and more effectively.  Upon reviewing hundreds of similar products, we were unable to find any other product that contains this combination let alone was backed by any sort of clinical supporting data.

Many companies who enjoy a positive reputation, take advantage of their good standing with the public in order to sell cheap health supplements. It’s so distressing how easy it is, which is why it is incumbent on every consumer to do their own fact-finding on any health product they purchase.

Approved Science MSM contains the purest MSM on the market in combination with a thermogenic ingredient to increase bioavailability in order to increase levels of sulfur throughout the body. This will help support joint health, reduce inflammation, promote muscle recovery, relieve allergy symptoms, improve skin health, boost the immune system and strengthen antioxidant defenses. What we really like is that it is made by a company that consistently uses clinical studies as a benchmark for the dosage of all their health supplements. There is also a money-back guarantee which can be claimed by speaking to their customer service agents who are real, not just bots!

Additionally, you will not find any ingredients in Approved Science MSM which shouldn’t be there. There are no added fillers, binders, additives or preservatives. There are so many products out there that do not fall within the realm of high standards, offering artificial alternatives and all sorts of extras inside their formulas. It is a relief to be able to recommend a company that manufactures such a unique, well-researched product.

To summarize, Approved Science MSM uses top-quality natural ingredients, provides awesome results, has a caring customer support team and a great price. From what we saw, without a doubt, this is an extremely good product.

Quality Assurance

Over the last few years, we understand how consumers have grown skeptical of nutritional health supplements. This simply comes down to shady companies providing useless formulas that contain unrelated and unuseful ingredients or that add fillers or binders to their products. Often, these ingredients are not pure, or have not been tested for quality and have no scientific validity as to why they have been included in the formulas. Not only is this irresponsible, but often quite dangerous. Truth being, there is absolutely no reason why anything artificial should be added. Natural and pure is the best.

On many nutritional supplements, the label states that the ingredients are either ‘active’ or inactive’. In simple terms, the active ingredients are the reason you decided to purchase the product and the ones that actually bring you the results you are hoping for. When you see a long list of inactive ingredients, beware, often companies will fill their products with unhelpful and potentially dangerous junk.

That is why, for us, Approved Science MSM is a product that does not fall within this category. Its formula contains only natural and pure ingredients backed by numerous clinical studies and research. It offers a simple philosophy that seems to work well – offer top-quality ingredients in the most effective potency, great price options with a terrific money-back guarantee and you won’t be disappointed.

Another aspect of taking supplements that contain a large amount of inactive or unnecessary ingredients is the lack of understanding of how these chemicals may affect existing medical conditions or medications. If the ingredients are bona fide and in their natural form, side effects or negative interactions are unlikely to be experienced.

We were very happy to discover that Approved Science MSM is manufactured in an FDA-registered facility. What’s more, is that it is cGMP recognized and complies with the US Pharmacopeia’s standards for quality and purity. This suggests that this company takes what it does very seriously, and strives to keep its products safe, natural and effective – a mentality that we totally appreciate.


Approved Science MSM comes at an affordable price with some excellent multiple purchase deals, allowing for huge cost savings for consumers. Also, this company is staunchly against any auto-ship programs, as they can be nearly impossible to cancel.

Nowadays, consumers need to be ‘smart shoppers’, carrying out as much research as they can about what they would like to purchase, in order to avoid wasting their money. There are many options out there that charge a lot of money for inferior products that simply will not deliver the results that they promise. This is disheartening and quite frankly, a bad and dishonest practice.

Orders are shipped within 24-hours, with the exclusion of any orders placed on weekends and holidays. They are wrapped and sent in discreet packaging, with no identifying marks on the outside, unlike other companies who often have embarrassing slogans or logos. Furthermore, this company provides a 60-day risk-free money-back guarantee. If you are not 100% happy with the results, you are able to return the product and receive a full refund. That shows strong confidence in its product and we totally support that kind of guarantee.

In Conclusion

When people are searching for a good MSM product, they may not realize that there is more to an effective MSM supplement than simply containing methylsulfonylmethane. It needs to contain the correct purity of MSM, in the right dose to be effectively utilized by the body.

Approved Science MSM specifically contains the optimal blend of ingredients which are clinically proven to make an MSM supplement effective. They are:

  • Contains OptiMSM®, a patented MSM clinically-proven and known world-wide for its purity, consistency and transparency.
  • Provides a powerful daily dose of 2000mg of MSM which is double the daily dose of most other supplements for optimal health benefits. 
  • Undergoes a proprietary, 4-stage distillation method of MSM for unrivaled purity devoid of contaminants.
  • Formulated with BioPerine®, a patented black pepper extract to enhance bioavailability for faster results.
  • Contains GRAS-designated OptiMSM®, the only MSM with this certification for safety and real results. 

Additionally, there are other significant elements to bear in mind, such as third-party testing and comprehensive customer reviews that give us a great indication of how the product really works.

Of all the products that we reviewed, across all parameters, none compared to Approved Science MSM. If you are looking for a top-quality formula backed by research and scientific data that is an effective, long-term solution to enhance joint flexibility, improve skin health, reduce inflammation and boost antioxidant benefits in the body, you would be hard pushed to find anything better than Approved Science MSM.

Approved Science MSM
Douglas Laboratories MSM Capsules
Designs for Health MSM
KALA Health MSMPure
Provides at least a 2,000mg daily serving of MSM
Contains OptiMSM®, GRAS-designated for purity
Does not include heavy metals, contaminants or impurities
Contains Ingredient for enhancing absorption and utilization of MSM
No additives, preservatives, or artificial ingredients
Made in the USA
Money-back guarantee

Read on to see what their happy customers are saying

“Approved Science MSM is a high quality MSM that is the best deal around. I had tried a powder MSM supplement for a cheaper option but it tasted so awful that I had to chuck it. MSM is vital as it supplements essential sulfur within our bodies. Most people don’t get enough MSM in their diets, I know I definitely don’t. Now that I started taking this great product, I am hooked. But, please beware that side effects can include healthier hair, nails, and skin! Don’t say you haven’t been warned!”  – Rose Mckee

“After breaking my knee 2 years ago, I developed pain and inflammation that stayed with me. I doubted that natural ingredients could help me when prescription meds didn’t, but I was willing to try anything. Approved Science MSM really surprised me. I took it religiously and my bones are so much stronger and healthier. The inflammation has gone down and my pain has rapidly diminished. This is an excellent product. I highly recommend trying it, even if you don’t have knee damage. I swear by Approved Science and will continue to use their MSM every day.” – Jimmy Villalobos

“Approved Science MSM is amazing for hair growth! I have been taking biotin from Approved Science for years and have been super happy. Once I started reading about MSM, I was interested to see if the combination of both products could give me even better results. I can definitely see that my hair is growing a lot faster than it used to. it’s also super shiny and healthy – I can see a lot fewer split ends. My skin really responded well to the MSM as well. It’s a lot less oily and I stopped getting that pesky acne from wearing masks. This is my favorite beauty product these days!” – Alaina Dimick       

“This product is a “must buy” on my list. I read that MSM could help with allergy symptoms and I am someone who is always sneezing from random allergens. It wasn’t just annoying, I was the one interrupting meetings and drawing unwanted attention. I tried a cheap brand of MSM that did nothing for me so I decided to invest in Approved Science to give it a real chance to work. And it did! I have not had any of my usual allergy attacks since! This just works for me. My friends noticed that my skin has looked really clear since taking it as well, which is a great bonus!”  – Veronica Hagen

“I suffer from arthritis in my neck so my range of motion is very limited. After taking Approved Science MSM, I was able to turn my head much more easily which has helped tremendously while driving. I also no longer have a stiff neck when I wake up. My sleep is so much better because of it. You can tell that it’s pure MSM, there is a clear difference between this and other brands. I noticed that I have more energy and that my skin looks more youthful. I was told about this product from a friend so I’m happy to pass on this information to anyone who could benefit as I have.”  – Cathy Edwards

“This MSM from Approved Science works wonders. I started to feel the pains of midlife right after I turned 45. My hair and knees seemed to give up at the same time. Instead of getting a cliched brand new red sports car, I revamped my diet and lifestyle to turn my life around. One of the best things I discovered was dietary supplements. My eyes used to glaze over the rows of bottles at the pharmacy but once I started to investigate and read the research, I needed to try them out for myself. Some supplements did nothing for me but others made a big difference. When it comes to MSM, it hit the most important issues for me – joints and hair. I am grateful to be able to exercise the way I want to and, although it may be vain, I love having a fuller head of hair. I recently put in an order for a bulk delivery and you can bet that I am a customer for life.” – Glen Shires          

“I took MSM for years but I ran out recently and just kind of forgot about it. A month or so went by and when I noticed that my joints were really bothering me I realized that the only change in my routine was that I hadn’t been taking MSM. I had never tried Approved Science MSM before but I had a discount code in my email so I gave it a whirl. To my delight, this formula works better and is less expensive than the brand I used to use. My joints are thanking me! I was also pleased with how fast and easy the delivery was. Overall, it was a wonderful experience. If you are someone who thinks aching joints are inevitable, try MSM. It makes a real difference in my life!” – Betty Chesser

FAQs about Approved Science MSM:

How does Approved Science MSM work?

The key lies in the purity of the methylsulfonylmethane (MSM) contained within this formula – there isn’t a list of ingredients that have been plucked from thin air so that they look good on the label! 100% pure and certified MSM is supported by clinical research for incredible health benefits! Made in the USA and manufactured in a cGMP-certified, ISO(International Organization for Standardization)-registered facility to ensure quality and safety.

What’s more, this product contains clinically-proven OptiMSM® for purity and consistency and contains a whopping 2000mg MSM for proven health benefits. This is double the amount found in other supplements. In addition, BioPerine®, a patented black pepper extract, is added to this formula to enhance bioavailability for faster results. No other MSM product has this unique combination. 

MSM is positively associated with helping to enhance joint flexibility, improve skin health, reduce inflammation and boost antioxidant activity to keep your body functioning at its best. The great thing is that this formula is all natural which means that it is safe for long-term use.

Do all MSM supplements work in a similar way?

The short answer is basically no, they do not. There are many companies that just ride the trends, producing inferior products with weak formulas in the wrong proportions. Many use incorrect ingredients, fillers, binders or even worse ingredients that can affect desired results, and even be dangerous.

What should I look for in an effective MSM supplement?

  • It should contain clinically-proven OptiMSM® for purity and consistency.
  • It should contain a daily dosage of 2000mg of MSM for optimal health benefits.
  • It should contain distilled, and not crystallized, MSM for 100% purity without any contaminants.f
  • It should contain a thermogenic ingredient that enhances the body’s ability to absorb and utilize MSM.
  • It should be GRAS-designated and manufactured in an FDA-registered laboratory for safety and transparency.
  • It should not contain any binders, fillers, additives, hormones, preservatives or artificial ingredients.
  • It must be 100% pure, natural and with no unnecessary ingredients that could reduce the effectiveness of the product.
  • It should be formulated using the same potency as found effective in clinical studies.

Are there any side effects noted when using this product?

Our research did not uncover any negative side effects when using this product. The ingredients that are contained within the formula of Approved Science MSM are all-natural and 100% pure. That said, as with any supplement, we always recommend consulting with a doctor if you are pregnant, breastfeeding, have an existing medical condition or are taking any other medication.

What are the dosage instructions for Approved Science MSM?

The manufacturers of this product suggest taking 2 capsules per day, preferably 30 minutes before mealtime with a glass of water. 

As with any supplement, always follow the recommended dosage instructions and do not exceed them as this poses health risks.

How long before I can see any results?

Results will vary for each person. For some, they will see changes almost immediately, for others it may take longer. It is different for each person. Other factors that affect results can include age, diet, and lifestyle so it is hard to say exactly. What you should look out for are those companies who offer a satisfaction guarantee. This suggests that they are confident that their products will deliver the desired results. And after all, if you don’t get the results you were hoping for you can always return the product. Approved Science MSM offers a great money-back guarantee and awesome feedback on how well this product works.

What price should I expect to pay?

The cost of products vary among manufacturers. Unfortunately, many are cheap, useless supplements that have been formulated without any science-based evidence to back them up. Some of these companies are selling their products for over $100 per bottle, which is very expensive. On average, the best supplements we found are selling between the $40-$50 price range. Often, when products appear cheaper, this is indicative of low quality or a low recommended daily serving, which will not bring the results you are looking for. Be aware. Read the labels.

Which MSM supplement should I buy?

As each person’s experience of a product is different, it is difficult to say specifically which one is the best. That said, based on several factors, we did like Approved Science MSM. We found that from the 50+ products that we looked at, Approved Science MSM had the best quality of ingredients, potency and strength, positive consumer feedback and the manufacturer’s customer service was excellent.

How safe is it to order over the internet?

Approved Science MSM is safe to be ordered over the internet. The manufacturer utilizes the latest encryption software to protect your credit card information and does not engage in shady schemes such as ‘automatic billing’ programs like many other companies do. They also deliver very efficiently and quickly, using discreet packaging.

Why should I choose Approved Science MSM?

There are several reasons why we liked this product including purity of ingredients, customer service, satisfaction, and effectiveness. Its formula is backed by clinical studies and we feel it values consumers’ health above and beyond the profit margins.

This is a great product that you can depend on. It has a well-researched formula with the right ingredients in the correct potency. And if that wasn’t enough, check out the customer reviews – they say it all. It counts with many happy customers clearly singing the praises of this trustworthy product who are highly loyal to this brand. We will summarize the key benefits one more time:

  • It provides a unique patented MSM, OptiMSM®, delivering the most effective form of MSM for optimal health benefits.
  • It contains a potent dosage of 2000mg of MSM which is double the daily dose of most other supplements. 
  • It contains MSM which has been distilled in a proprietary 4-stage process to ensure zero impurities.  
  • It contains BioPerine®, a patented black pepper extract proven to increase nutrient absorption for faster, more effective results. 
  • It contains GRAS-designation for the clinically-proven purest MSM.
  • It does not contain any preservatives, artificial colorings, hormones, or unnecessary ingredients that may dilute the efficacy of the product.
  • Its lab is FDA and cGMP recognized.
  • Its products comply with the standards for quality and purity outlined by the U.S. Pharmacopeia
  • This product is well priced and falls below average when compared to other similar products. The manufacturer of Approved Science MSM also provides some great discounts for multiple purchases, which can save consumers a lot of money.
  • Our research showed that the company is trustworthy, reliable, transparent and has integrity and a great reputation in the industry.
  • The manufacturer of Approved Science MSM offers a great 60-day money-back guarantee which can be utilized, no questions asked if you are not happy with the results. This shows that the manufacturer has strong confidence in its products’ ability to garner effective results.

The Bottom Line

At the end of the day, the bottom line is that consumers have so many options when choosing a health supplement. We are constantly being bombarded with commercials, advertisements and messages about so many different products, for varying health issues that it is beyond confusing which ones are the real deal and which ones are a waste of time. MSM supplements are no exception, with many companies simply trying to cash in on the latest health trends and pushing their products on unwilling consumers.

We like Approved Science MSM because we feel that this company is different. It is in it for the long haul. It has researched its ingredients well and produced its formula using only pure natural ingredients with a lot of clinical data to back them up. The manufacturer of Approved Science MSM offers what more companies should – an effective, affordable product supported by a real concern for the health of their customers. As an added bonus, Approved Science MSM has many happy testimonials to support our belief that this is a great product and a great company.   

What You’ll Discover:

Which MSM supplement is the BEST BUY and comes with a great GUARANTEE!
Which formula and ingredients are the most EFFECTIVE and work the fastest?
How NOT to get ripped off! BE AWARE of poor quality and cheap products.

Top 6 Items to Consider:

  1. Ingredients
  2. Cost Per Serving
  3. Product’s Testing Results
  4. Company’s Reputation
  5. Consumer Reviews
  6. Return Policy & Satisfaction Guarantee

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